How STEGLATRO Works

STEGLATRO helps your kidneys remove some sugar.

See below to learn how STEGLATRO helps your kidneys get rid of some sugar from your body and flush it out through your body’s process of urination.

• = Blood Sugar

Welcome to the kidneys

The kidneys act as a filter for the blood in your body. They filter out waste, and also some nutrients. Then, they return back to the bloodstream the nutrients you need, including sugar for energy, and send the waste into the urine.

The kidneys and type 2 diabetes

If you have type 2 diabetes, you have too much sugar in your blood. Your kidneys will filter out waste and some sugar, but they will also allow some sugar to return to your bloodstream and body.

See How Kidneys Work When You Have Type 2 Diabetes

Learn How STEGLATRO® (ertugliflozin) Works

How STEGLATRO can help!

STEGLATRO helps lower blood sugar levels by reducing the amount of sugar the kidneys return to the bloodstream and increasing the amount of sugar that is removed from the body through the urine. So over time, when you go, so does some sugar, which may help you lower your A1C.

See How STEGLATRO® (ertugliflozin) Works

Important Safety Information

Do not take STEGLATRO if you:

are allergic to ertugliflozin or any of the ingredients in STEGLATRO. Symptoms of a serious allergic reaction to STEGLATRO may include skin rash, raised red patches on your skin (hives), and swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. If you have any symptoms of a serious allergic reaction, stop taking STEGLATRO and call your doctor right away.
are on dialysis.

STEGLATRO may cause serious side effects including:

Ketoacidosis (increased ketones in the blood or urine) has happened in people with type 1 or type 2 diabetes during treatment and also in people with diabetes who were sick or who had surgery during treatment with STEGLATRO. Ketoacidosis is a serious condition, which may need to be treated in a hospital and may lead to death. Ketoacidosis can happen even if your blood sugar is less than 250 mg/dL. Symptoms may include nausea, vomiting, stomach-area (abdominal) pain, tiredness, and trouble breathing. If you get any of these symptoms, stop taking STEGLATRO and call your doctor right away. If possible, check for ketones in your urine, even if your blood sugar is less than 250 mg/dL.

Amputations. STEGLATRO may increase your risk of lower limb amputations. You may be at a higher risk of lower limb amputation if you: have a history of amputation; have had blocked or narrowed blood vessels, usually in your leg; have damage to the nerves (neuropathy) in your leg; have had diabetic foot ulcers or sores. Call your doctor right away if you have new pain or tenderness, any sores, ulcers, or infections in your leg or foot. Your doctor may decide to stop your STEGLATRO for a while if you have any of these signs or symptoms. Talk to your doctor about proper foot care.

How STEGLATRO Works

What is STEGLATRO?

Important Safety Information

Important Safety Information

Important Safety Information